Dopamine Psychosis

Many people with schizophrenia have an increased ability to produce dopamine and appear to release unusually high quantities of dopamine during nerve cell activity. We know this from PET studies that can measure dopamine synthesis in the brains of living human volunteers, and from measures of dopamine metabolites in volunteers.

This short lecture, presented to the SZconsult community on 22 January 2019, will consider the role of dopamine in producing symptoms of psychosis, and will suggest that: in the treatment of psychosis, a little bit of dopamine blocking can a useful tool; but too much dopamine blocking should be avoided.

Here are the slides