Depression and Schizophrenia

This lecture explores the intersection between the symptoms of depression and the symptoms of schizophrenia.


This lecture begins by questioning the separateness of mood disorders and schizophrenia.

The idea that mood disorders are separate from the schizophrenias is a 19th century concept. But how valid is this distinction in view of 21st century science?


There are actually several levels of overlap between depression and schizophrenia.

The so-called negative symptoms of schizophrenia are very similar to symptoms of depression.

There are also many genes in common between these two conditions.

Many people with depression benefit from antipsychotic medications. And many people with schizophrenia benefit from antidepressant medications.


Here are the slides: Depression and Schizophrenia